Nasal drug delivery to the cerebrospinal fluid: transport of a lipophilic compound
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چکیده
منابع مشابه
from linguistics to literature: a linguistic approach to the study of linguistic deviations in the turkish divan of shahriar
chapter i provides an overview of structural linguistics and touches upon the saussurean dichotomies with the final goal of exploring their relevance to the stylistic studies of literature. to provide evidence for the singificance of the study, chapter ii deals with the controversial issue of linguistics and literature, and presents opposing views which, at the same time, have been central to t...
15 صفحه اولSimulation of cerebrospinal fluid transport
The model consists of 5 compartments (indicated by integer 1-5). In accordance with literature, cardiac related pulsations is introduced intracranially (by means of B “pseudo” compartment) while the respiration related pulsation is introduced spinally from spinal epidural space (C, T and L). We assume an isothermal flow of an ideal fluid. The model equations are derived by invoking basic conser...
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The textbook view that projections of the arachnoid membrane into the cranial venous sinuses represent the primary cerebrospinal fluid (CSF) absorption sites seems incompatible with many clinical and experimental observations. On balance, there is more quantitative evidence suggesting a function for extracranial lymphatic vessels than exists to support a role for arachnoid villi and granulation...
متن کاملA Giant Abdominal Cerebrospinal Fluid Pseudocyst
Background and Aim: Ventriculoperitoneal shunt (VPS) is the most commonly used procedure for treatment of hydrocephalus in children. Abdominal cerebrospinal fluid pseudocyst is a rare complication but potentially fatal. The pathogenesis of this complication remains unclear. This complication should be considered during differential diagnosis of an abdominal mass. Our aim is to report how large ...
متن کاملCerebrospinal Fluid Indices in Acute Drug Intoxication Do they Predict the Patients’ Outcome?
Introduction: In some intoxicated patients, cerebrospinal fluid (CSF) is examined due to the prolonged loss of consciousness, focal neurologic findings, and fever of unknown origin. We aimed to evaluate the probable relationship between the different toxicity causes and the CSF indices in poisoned patients and determine if they could predict the patients’ outcome. Methods: All patients who h...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2002
ISSN: 0306-5251,1365-2125
DOI: 10.1046/j.1365-2125.2002.t01-2-01714.x